7 Most Popular Diet Pills That Work Fast Without Exercise

2. Contrave (bupropion and naltrexone) – Orexigen Therapeutics, Inc. (NASDAQ:OREX)

Contrave’s two ingredients are both effective at decreasing appetite and/or food cravings, making the combination ideal for people who struggle with controlling their caloric intake. Three studies showed that Contrave helped reduce weight by as much as four-times more than without the drug, in combination with diet and exercise changes. Given that Contrave’s ingredients are also used in anti-depressants and smoking cessation aids, taking it could even help you overcome those issues, though it is not approved for the treatment of them. It should be noted that Contrave cannot be used in combination with a high-fat diet (Atkins, ketogenic), or taken with any high-fat meal, as the odds of having a seizure are greatly increased. Orexigen Therapeutics, Inc. (NASDAQ:OREX) bought the U.S rights to Contrave back from Japanese partner Takeda Pharmaceuticals in mid-2016.

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