2. St. Louis, Missouri
Violent crime rate: 1,913 per 100,000 residents
The most striking factor about St. Louis that ranks 2nd in our list of most lawless places in the US is that it has the highest murder rate nationwide. Although it has been placed second for having a marginally less violent crime rate, if this list was about murder rates in America, St. Louis would have easily topped it. Gun-related violence in St. Louis is also very high in comparison. If you are wondering, the murder rate of St. Louis is about 60 per 100,000 residents, which is at least ten times more than the national average. If things do not change there, the situation will only get worse.