5 New Alternatives to Antibiotics: Alternative Therapeutic Strategies to Treat Antibiotic-Resistant Pathogens

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1. Antimicrobial Peptides 

Insider Monkey Score: 1 

Antimicrobial peptides (AMPs) are emerging as potent alternatives to antibiotics: alternative therapeutic strategies to treat antibiotic-resistant pathogens , with over 3257 described to date from various sources. They exhibit broad-spectrum antimicrobial activity against bacteria, fungi, and viruses and show promise in combating antimicrobial resistance (AMR)—AMPs work by disrupting microbial cell membranes, inhibiting cell wall synthesis, or targeting intracellular components. Challenges include high production costs, susceptibility to protease digestion, and concerns about toxicity. However, research on combination therapies is promising for reducing cytotoxicity and enhancing efficacy against resistant bacteria.  

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