5 Most Populated Countries in South America

2. Colombia 

Population as of 2022: 51,874,024 people 

Colombia is located in northwestern South America with around 1600 kilometers of its northern coast touching the Caribbean Sea. Its 1300-kilometer-long western coast touches the Pacific Ocean. Colombia has a population of 51,874,024 people as of 2022, according to estimates by the World Bank. That makes it the second most populated country in South America after Brazil, despite a significant difference in the populations of the two countries.