5 Best-Performing Stocks in the Last 12 Months

In this article, we will take a look at the 5 best-performing stocks in the last 12 months. To see more such companies, go directly to 15 Best-Performing Stocks in the Last 12 Months.

5. United Insurance Holdings Corp. (NASDAQ:UIHC)

Share Price Gains Over the Past 12 Months Through August 11: 586%

Property and casualty insurance company United Insurance Holdings Corp. (NASDAQ:UIHC) has been one of the best-performing stocks over the past one year. It has gained about 586% over the past 12 months.

Earlier in August United Insurance Holdings Corp. (NASDAQ:UIHC) posted Q2 results. Adjusted EPS in the quarter came in at $0.65. Revenue in the quarter jumped about 24.1% year over year to $79.3 million.

As of the end of the first quarter of 2023, 3 hedge funds in Insider Monkey’s database had stakes in United Insurance Holdings Corp. (NASDAQ:UIHC).

4. Reata Pharmaceuticals, Inc. (NASDAQ:RETA)

Share Price Gains Over the Past 12 Months Through August 11: 696%

Plano, Texas-based Reata Pharmaceuticals, Inc. (NASDAQ:RETA) ranks 4th in our list of the best-performing stocks over the past 12 months. Reata Pharmaceuticals, Inc. (NASDAQ:RETA) has gained about 696% over the past one year. Reata Pharmaceuticals, Inc. (NASDAQ:RETA) makes oral antioxidative and anti-inflammatory drugs.

As of the end of the first quarter of 2023, 31 hedge funds tracked by Insider Monkey reported owning stakes in Reata Pharmaceuticals, Inc. (NASDAQ:RETA). The biggest stakeholder of Reata Pharmaceuticals, Inc. (NASDAQ:RETA) during this period was Joseph Edelman’s Perceptive Advisors which had a $197 million stake in the company.

3. Applied Optoelectronics, Inc. (NASDAQ:AAOI)

Share Price Gains Over the Past 12 Months Through August 11: 556%

Texas-based Applied Optoelectronics, Inc. (NASDAQ:AAOI) makes fiber-optic networking products. It is one of the best-performing stocks in the last 12 months since it has gone up by 556% in the period.

Applied Optoelectronics, Inc. (NASDAQ:AAOI) shares jumped earlier in August after the stock was upgraded by B. Riley Securities to Buy from Neutral. Applied Optoelectronics, Inc. (NASDAQ:AAOI) cited improving demand and margins for the upgrade and hiked its price target to $11.50 from $2.50.

2. Cabaletta Bio, Inc. (NASDAQ:CABA)

Share Price Gains Over the Past 12 Months Through August 11: 746%

Clinical-stage biotechnology company Cabaletta Bio, Inc. (NASDAQ:CABA) works on T-cell therapies for patients with B cell-mediated autoimmune diseases.

Cabaletta Bio, Inc. (NASDAQ:CABA) has gained about 746% over the past 12 months. As of the end of the first quarter of 2023, 17 hedge funds tracked by Insider Monkey were long Cabaletta Bio, Inc. (NASDAQ:CABA). The biggest stakeholder of Cabaletta Bio, Inc. (NASDAQ:CABA) during this period was Phill Gross and Robert Atchinson’s Adage Capital Management with a $21 million stake in the company.

1. MoonLake Immunotherapeutics (NASDAQ:MLTX)

Share Price Gains Over the Past 12 Months Through August 11: 841%

Swiss biopharmaceutical company MoonLake Immunotherapeutics (NASDAQ:MLTX) ranks 1st in our list of the best-performing stocks over the past year. MoonLake Immunotherapeutics (NASDAQ:MLTX) has gained about 841% over the past one year. MoonLake Immunotherapeutics (NASDAQ:MLTX) is working on treatments for inflammatory diseases. In July, MoonLake Immunotherapeutics (NASDAQ:MLTX) jumped after Reuters reported that the company was working with an investment bank following early-stage discussions with drugmakers interested in buying the company.

As of the end of the first quarter of 2023, 16 hedge funds out of the 943 funds tracked by Insider Monkey had stakes in MoonLake Immunotherapeutics (NASDAQ:MLTX).

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