20 Cities With the Highest HIV/AIDS Rates in the US

4. Miami-Fort Lauderdale-Pompano Beach, Florida 

Average Rate of HIV and AIDS per 100,000: 799%

AIDS Rate per 100,000: 518%

HIV Rate per 100,000: 1080%

HIV Cases: 57,097

AIDS Cases: 27,383

The Miami-Fort Lauderdale-Pompano Beach Metropolitan Statistical Area ranks 4th on our list of cities with the highest HIV/AIDS rates in the US. It had 57,097 HIV cases and 27,383 AIDS cases in 2022.