12. Melville, Louisiana
Population: 1,041
Median Household Income: $14,328
Atchafalaya River Catfish Capital of Louisiana doesn’t have much else to offer except fishing. Back in a day, it was one of the most important industries in town and some 50 barrels of fish were shipped daily, and now it is just one of the poorest neighborhoods in America. Highway 105, famous for the last scene from Easy Riders, goes through town.