3. West Memphis, Arkansas
Total STDs: 859
Total STDs per 100,000: 1717.29
You should note that West Memphis was viewed separately from Memphis metropolitan area, which contributed to its high STDs per 100,000 rate although it has the lowest total number of STDs compared to other entries on the list of most sexually diseased cities in America. The city has a population just above 50,000, with 634 of them suffering from chlamydia. Gonorrhea accounts for 220 of all STD cases while there are 5 persons infected with syphilis.

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