15 Small-Cap Stocks Poised to Outperform in 2025

Fifteen small-cap stocks—predominantly under the technology sector—are taking center stage this year, boasting triple- to quadruple-digit performance in their share prices, thanks to the booming Artificial Intelligence sector.

In this article, we will dive into their performance and evaluate whether these stocks are poised to become the next big winners for your portfolio.

To come up with the 15 hottest small-cap stocks, we only considered companies with more than $3 million in trading volume and less than $2 billion in market capitalization.

A person with stock market data on a laptop. Photo by Anna Nekrashevich on Pexels

15. AmpliTech Group Inc. (NASDAQ:AMPG)

AmpliTech Group’s involvement in the Artificial Intelligence (AI) boom sent the company’s share prices soaring by nearly 200 percent over the past five years, and by 101.01 percent in the past 52 weeks.

The company’s stellar five- and one-year performances were reflective of investors’ confidence in the company—despite not being profitable yet—over expectations that it is one of the many technology companies to ride the booming AI industry.

In recent news, AmpliTech earlier received another Notice of Allowance from the US Patent and Trademark Office for its patent application related to MMIC LNA Designs.

Upon issuance, AmpliTech will then have three key patents, all of which are expected to strengthen its position in producing systems and components for 5G, Quantum Computing, and Satellite communication industries.

14. Quantum-Si Inc. (NASDAQ:QSI)

Quantum-Si, a protein sequencing platform, offers semiconductor chips designed to enable single-molecule next-generation protein sequencing and genomics and digitize proteomic research in order to advance drug discovery and diagnostics beyond DNA sequencing.

Over the past year, investors have posted confidence in the company’s prospects, as reflected in a 100-percent increase in its 52-week price to $4.10 per share.

Its earnings performance is also beginning to reflect its growth potential, with quarterly revenues soaring by 252.9 percent year-on-year to $787,000 while gross profit similarly rose by 239 percent during the same period.

Just recently, Quantum-Si entered into a series of partnerships with Avantor, for its NGPS portfolio in the US and Canadian markets, and with Planet Innovation to commercialize the Platinum Pro by mid-2025, alongside continued development of the Proteus platform.

Quantum-Si’s unique business as a platform provider rather than a pharmaceutical player positions its stability and scalability. As long as the company maintains consistent revenue growth and strong institutional backing, the company will continue to present a compelling investment opportunity.