10. Rome, Italy
Average Cost Per Week: $997
Next on our list of most expensive cities to spend a week in Europe we have Rome that is one of the oldest cities in Europe, and this shows as you travel across the alleyways of Rome. You will come upon many historical landmarks like the Colosseum, The Roman Forum, the Vatican Museums and many more. Rome also is a bustling modern city full of everything you expect from such a city. Active nightlife, awesome dining, clubs, and pubs, you can find it all in Rome.