13G Filing: Perceptive Advisors and Quotient Ltd (QTNT)

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Explanatory Note

Amendment No. 1 to the Schedule 13G filed by the Reporting Persons on October 26, 2017 inadvertently misstated the number of shares of Common Stock
directly held by the Master Fund and that may be deemed beneficially owned by Mr. Edelman and Perceptive Advisors. This Amendment No. 2 to the Schedule 13G corrects that number.

Item 1(a).

Name of Issuer:

Quotient Limited (the Issuer)

Item 1(b).

Address of Issuers Principal Executive Offices:

B1, Business Park Terre
Bonne, Route de Crassier 13, 1262 Eysins, Switzerland

Item 2(a).

Names of Persons Filing:

The names of the persons filing this report
(collectively, the Reporting Persons) are:

Perceptive Advisors LLC (Perceptive Advisors)

Joseph Edelman (Mr. Edelman)

Perceptive Life Sciences Master Fund, Ltd. (the Master Fund)

Item 2(b).

Address of Principal Business Office or, if None, Residence:

The address of the
principal business office of each of the Reporting Persons is:

51 Astor Place, 10th Floor

New York, NY 10003

Item 2(c).

Citizenship:

Perceptive Advisors is a Delaware limited liability company

Mr. Edelman is a United States citizen

The Master Fund is a Cayman Islands corporation

Item 2(d).

Title of Class of Securities:

Ordinary Shares, nil par value (Common
Stock)

Item 2(e).

CUSIP Number:

G73268 10 7

Item 3.

If this statement is filed pursuant to §§ 240.13d-1(b) or 240.13d-2(b) or (c), check whether the person filing is a:

Not applicable.