13G Filing: James E. Flynn and Biocryst Pharmaceuticals Inc (BCRX)

Provide the following information regarding the aggregate number and percentage of the class of securities of the issuer identified in Item 1.

Deerfield
Mgmt, L.P. – 5,478,719 shares

Deerfield Management
Company, L.P. – 5,478,719 shares

Deerfield Partners,
L.P. – 2,242,977 shares

Deerfield International
Master Fund, L.P. – 2,860,732 shares

Deerfield
Special Situations Fund, L.P. – 375,010 shares

James E. Flynn – 5,478,719
shares

Deerfield
Mgmt, L.P. – 6.81%

Deerfield Management
Company, L.P. – 6.81%

Deerfield Partners,
L.P. – 2.79%

Deerfield International
Master Fund, L.P. – 3.56%

Deerfield
Special Situations Fund, L.P. – 0.47%

James E. Flynn – 6.81%

Deerfield Mgmt, L.P.
– 5,478,719

Deerfield Management
Company, L.P. – 5,478,719

Deerfield Partners,
L.P. – 2,242,977

Deerfield International
Master Fund, L.P. – 2,860,732

Deerfield
Special Situations Fund, L.P. – 375,010

James E. Flynn – 5,478,719

Sole power to dispose or to direct the disposition of:

Shared power to dispose or to direct the disposition
of:

Deerfield Mgmt, L.P.
– 5,478,719

Deerfield Management
Company, L.P. – 5,478,719

Deerfield Partners,
L.P. – 2,242,977

Deerfield International
Master Fund, L.P. – 2,860,732

Deerfield
Special Situations Fund, L.P. – 375,010

James E. Flynn – 5,478,719