13G Filing: Baker Bros. Advisors and Bellicum Pharmaceuticals Inc (NASDAQ:BLCM)

Schedule 13G

Baker Bros. Advisors LP (the “Adviser”), Baker Bros.
Advisors (GP) LLC (the “Adviser GP”), Julian C. Baker and Felix J. Baker (collectively, the “Reporting Persons”)
have previously filed reports on Schedule 13D.  As of the date hereof, the Reporting Persons hold securities of Bellicum Pharmaceuticals,
Inc. (the “Issuer”) in the ordinary course of business without the purpose of or with the effect of changing or influencing
the control of the Issuer and do not hold such securities in connection with or as a participant in any transaction having that
purpose or effect.

The Reporting Persons’ previous filings on Schedule 13D
should not be deemed an admission that the Reporting Persons previously held securities of the Issuer otherwise than in the ordinary
course of business without the purpose of or with the effect of changing or influencing the control of the Issuer or that the Reporting
Persons previously held such securities in connection with or as a participant in any transaction having that purpose or effect.

 

Item 1(a)

Name of Issuer:

Bellicum
Pharmaceuticals, Inc.

Item 1(b)

Address of Issuer’s Principal Executive Offices:

2130 W. Holcombe Blvd., Ste. 800

Houston, Texas 77030

Item 2(a)

Name of Person Filing:

This
Schedule 13G is being filed jointly by the Adviser, the Adviser GP, Felix J. Baker and Julian C. Baker (collectively, the “Reporting
Persons”).

Item 2(b)

Address of Principal Business Office or, if None, Residence:

The business
address of each of the Reporting Persons is:

c/o Baker Bros. Advisors LP

667 Madison Avenue, 21^st
Floor

New York, NY 10065

(212) 339-5690

Item 2(c)

Citizenship:

The Adviser
is a limited partnership organized under the laws of the State of Delaware. The Adviser GP is a limited liability company organized
under the laws of the State of Delaware. The citizenship of each of Julian C. Baker and Felix J. Baker is the United States of
America.