13D Filing: James E. Flynn and Proteon Therapeutics Inc (PRTO)

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Page 16 of 17 – SEC Filing

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SIGNATURE

After reasonable inquiry
and to the best of their knowledge and belief, the undersigned certify that the information set forth in this statement is true,
complete and correct.


Dated: December 4, 2017

DEERFIELD
MGMT, L.P.

By: J.E. Flynn Capital, LLC, General Partner

By:
/s/ Jonathan Isler

Name: Jonathan Isler

Title: Attorney-in-Fact

DEERFIELD
MGMT III, L.P.

By: J.E. Flynn Capital III, LLC, General Partner

By:
/s/ Jonathan Isler

Name: Jonathan Isler

Title: Attorney-in-Fact

DEERFIELD
MGMT IV, L.P.

By: J.E. Flynn Capital IV, LLC, General Partner

By:
/s/ Jonathan Isler

Name: Jonathan Isler

Title: Attorney-in-Fact

DEERFIELD
INTERNATIONAL MASTER FUND, L.P.

By:
Deerfield Mgmt, L.P., General Partner

By: J.E. Flynn Capital, LLC, General Partner

By:
/s/ Jonathan Isler

Name: Jonathan Isler

Title: Attorney-in-Fact

DEERFIELD
SPECIAL SITUATIONS FUND, L.P.

By:
Deerfield Mgmt, L.P., General Partner

By: J.E. Flynn Capital, LLC, General Partner

By:
/s/ Jonathan Isler

Name: Jonathan Isler

Title: Attorney-in-Fact

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