13D Filing: James E. Flynn and Alpine Immune Sciences Inc. (ALPN)

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Page 13 of 13 – SEC Filing

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DEERFIELD PRIVATE DESIGN FUND II, L.P.

By: Deerfield Mgmt,
L.P., General Partner

By: J.E. Flynn Capital, LLC, General Partner

By: /s/ Jonathan
Isler

Name: Jonathan
Isler

Title: Attorney-in-Fact

DEERFIELD PRIVATE DESIGN INTERNATIONAL II, L.P.

By: Deerfield Mgmt,
L.P., General Partner

By: J.E. Flynn Capital, LLC, General Partner

By: /s/ Jonathan
Isler

Name: Jonathan
Isler

Title: Attorney-in-Fact

DEERFIELD MANAGEMENT COMPANY, L.P.

By: Flynn Management LLC, General Partner

By: /s/ Jonathan
Isler

Name: Jonathan
Isler

Title: Attorney-in-Fact

JAMES E. FLYNN

/s/ Jonathan Isler

Jonathan Isler, Attorney-in-Fact

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