13D Filing: Baker Bros. Advisors and Genomic Health Inc (GHDX)

The Funds hold securities of the Issuer for investment purposes.
The Reporting Persons or their affiliates may purchase additional securities of the Issuer or dispose of securities in varying
amounts and at varying times depending upon the Reporting Persons’ continuing assessments of pertinent factors, including
the availability of shares of common stock or other securities for purchase at particular price levels, the business prospects
of the Issuer, other business investment opportunities, economic conditions, stock market conditions, money market conditions,
the attitudes and actions of the Board and management of the Issuer, the availability and nature of opportunities to dispose of
shares of the Issuer and other plans and requirements of the particular entities. The Reporting Persons may discuss items of mutual
interest with the Issuer, which could include items in subparagraphs (a) through (j) of Item 4 of Schedule 13D.

Depending upon their assessments of the above factors, the Reporting
Persons or their affiliates may change their present intentions as stated above and they may make suggestions to the management
of the Issuer regarding financing, and may acquire additional securities of the Issuer, including shares of common stock (by means
of open market purchases, privately negotiated purchases, exercise of some or all of the Stock Options (as defined below), or otherwise)
or may dispose of some or all of the securities of the Issuer, including shares of common stock, under their control.

Except as otherwise disclosed herein, at the present time, the
Reporting Persons do not have any plans or proposals with respect to any extraordinary corporate transaction involving the Issuer
including, without limitation, those matters described in subparagraphs (a) through (j) of Item 4 of Schedule 13D.

Item 5 of this Schedule 13D is hereby amended and restated in
its entirety as follows:

(a) and (b) Items 7 through 11 and 13 of each
of the cover pages of this Amendment No. 32 are incorporated herein by reference. Set forth below is the aggregate number of shares
of common stock of the Issuer directly held by each of the Funds and the percentage of the Issuer’s outstanding shares of
common stock such holdings represent. The information set forth below is based upon 34,342,231 shares of common stock outstanding
as of April 30, 2017, as reported in the Issuer’s Form 10-Q filed with the SEC on May 10, 2017. Such percentage figures are
calculated in accordance with Rule 13d-3 under the Securities Exchange Act of 1934, as amended.

The Adviser GP, Felix J. Baker and Julian
C. Baker as principals of the Adviser GP, and the Adviser may be deemed to be beneficial owners of securities of the Issuer directly
held by the Funds, and may be deemed to have the power to vote or direct the vote of and the power to dispose or direct the disposition
of such securities. Julian C. Baker and Felix J. Baker are also the sole partners of FBB, a general partnership, and as such may
be deemed to be beneficial owners of shares of common stock directly held by FBB and may be deemed to have the power to vote or
direct the vote and dispose or direct the disposition of those shares.