13D Filing: Baker Bros. Advisors and Aquinox Pharmaceuticals Inc (NASDAQ:AQXP)

1.

NAMES OF REPORTING PERSONS

Baker Bros. Advisors LP

2.

CHECK
THE APPROPRIATE BOX IF A MEMBER OF A GROUP*

(a)
p

(b) p

3.

SEC USE ONLY

4.

SOURCE OF FUNDS*

OO

5.

CHECK
BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT TO ITEM 2(d) or 2(e) o

6.

CITIZENSHIP OR PLACE OF ORGANIZATION

Delaware

NUMBER OF
SHARES
BENEFICIALLY
OWNED BY EACH
REPORTING
PERSON WITH

7.

SOLE VOTING POWER 10,934,154

8.

SHARED VOTING POWER: 0

9.

SOLE DISPOSITIVE POWER: 10,934,154

10.

SHARED DISPOSITIVE POWER: 0

11.

AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON:
10,934,154

12.

CHECK
BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES CERTAIN SHARES (See Instructions) p

13.

PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)

46.7%(1)

14.

TYPE OF REPORTING PERSON (See Instructions)

IA, PN

Page 2 of 8 – SEC Filing

1.	NAMES OF REPORTING PERSONS Baker Bros. Advisors LP
2.	CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP* (a) p (b) p
3.	SEC USE ONLY
4.	SOURCE OF FUNDS* OO
5.	CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT TO ITEM 2(d) or 2(e) o
6.	CITIZENSHIP OR PLACE OF ORGANIZATION Delaware
NUMBER OF SHARES BENEFICIALLY OWNED BY EACH REPORTING PERSON WITH		7.	SOLE VOTING POWER 10,934,154
		8.	SHARED VOTING POWER: 0
		9.	SOLE DISPOSITIVE POWER: 10,934,154
		10.	SHARED DISPOSITIVE POWER: 0
11.	AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON: 10,934,154
12.	CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES CERTAIN SHARES (See Instructions) p
13.	PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11) 46.7%(1)
14.	TYPE OF REPORTING PERSON (See Instructions) IA, PN