13D Filing: Adage Capital Management and Inotek Pharmaceuticals Corp (ITEK)

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Page 13 of 13 – SEC Filing

EXHIBIT 1

JOINT FILING AGREEMENT
PURSUANT TO RULE 13d-1(k)

The undersigned
acknowledge and agree that the foregoing statement on Schedule 13D is filed on behalf of each of the undersigned and that all subsequent
amendments to this statement on Schedule 13D shall be filed on behalf of each of the undersigned without the necessity of filing
additional joint filing agreements. The undersigned acknowledge that each shall be responsible for the timely filing of such amendments,
and for the completeness and accuracy of the information concerning him or it contained herein and therein, but shall not be responsible
for the completeness and accuracy of the information concerning the others, except to the extent that he or it knows or has reason
to believe that such information is inaccurate.

DATE: October 5, 2017

 

ADAGE CAPITAL PARTNERS, L.P.
By:  Adage Capital Partners GP, L.L.C.,
its general partner
By:  Adage Capital Advisors, L.L.C.,
its managing member
/s/ Robert Atchinson
Name:  Robert Atchinson
Title: Managing Member
ADAGE CAPITAL PARTNERS GP, L.L.C.
By:  Adage Capital Advisors, L.L.C.,
its managing member
/s/ Robert Atchinson
Name:  Robert Atchinson
Title: Managing Member
ADAGE CAPITAL ADVISORS, L.L.C.
/s/ Robert Atchinson
Name:  Robert Atchinson
Title: Managing Member
ROBERT ATCHINSON
/s/ Robert Atchinson
ROBERT ATCHINSON, individually
PHILLIP GROSS
/s/ Phillip Gross
PHILLIP GROSS, individually

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