13D Filing: Adage Capital Management and Inotek Pharmaceuticals Corp (ITEK)

Schedule
A

Transactions in shares of Common Stock of
the Issuer since the filing of the Original Schedule 13D

The following table sets
forth all transactions in the shares of Common Stock effected by ACP since the filing of the Original Schedule 13D by the Reporting
Persons. All transactions were effectuated in the open market through a broker. The price reported in the column Price Per Share
($) is a weighted average price if a price range is indicated in the column Price Range ($). These shares of Common Stock were
purchased/sold in multiple transactions at prices between the price ranges below. The Reporting Persons will undertake to provide
to the staff of the SEC, upon request, full information regarding the number of shares of Common Stock sold at each separate price.

*       Excluding
commissions