10. San Jose, Costa Rica
At number 10 on our list of best places to visit in Central and South America in May, we again have a city from Costa Rica. San Jose is not just any city though, as it is the very capital of Costa Rica. Any list you come across detailing the best places to visit in Central America will have San Jose listed since this place is so good. Yes, it is a bit expensive compared to other central American tourist destinations, but the cost is outweighed by its natural beauty and cultural significance for sure.