11 Reddit Stocks with Biggest Upside Potential

2. Altimmune Inc. (NASDAQ:ALT)

Average Upside Potential as of November 11: 167.76%

Altimmune Inc. (NASDAQ:ALT) is a clinical-stage biopharmaceutical company that develops peptide-based therapeutics for obesity and liver diseases. Its lead drug, Pemvidutide, targets obesity and liver inflammation.

The company reported positive developments for its drug candidate Pemvidutide, a novel GLP-1/glucagon dual agonist in its obesity program, designed to treat obesity and metabolic dysfunction-associated steatohepatitis (MASH). It finished enrolling patients in its Phase 2b IMPACT trial (~190 people). This trial assesses Pemvidutide’s effectiveness and safety in treating MASH. Top-line data on the drug’s success is expected in the second quarter of 2025. If successful, Pemvidutide could become the first MASH treatment to achieve both reduced liver fat and significant weight loss within 24 weeks.

Overall, it has finalized the design of four pivotal Phase 3 trials with the FDA  to assess the impact on obesity-related comorbidities. Additionally, data from a Phase 2 study highlighted its ability to reduce body fat by 21.9% while preserving lean muscle mass, especially in older adults. To expand Pemvidutide’s potential, the company plans to submit IND applications for up to three additional indications by the end of 2024, with the first trial anticipated to start in H1 2025.

Altimmune Inc. (NASDAQ:ALT) is confident that 2025 will be a significant year for Pemvidutide and the company based on the progress made and upcoming milestones.