11 Most Promising Small-Cap Stocks According to Analysts

1. Dyne Therapeutics Inc. (NASDAQ:DYN)

Market Capitalization as of April 23: $1.26 billion

Number of Hedge Fund Holders: 41

Average Upside Potential as of April 23: 351.88%

Dyne Therapeutics Inc. (NASDAQ:DYN) is a clinical-stage neuromuscular disease company that operates as a biotechnology company that is advancing therapeutics for genetically driven muscle diseases in the US. It’s developing a portfolio of muscle disease therapeutics with the help of its FORCE platform that delivers disease-modifying therapeutics.

The company’s DYNE-251 program is a key focus for the company and targets individuals with Duchenne Muscular Dystrophy (DMD) who are amenable to exon 51 skipping. Data from the ongoing Phase 1/2 DELIVER trial has shown near-full-length dystrophin expression. Patients treated with the selected registrational dose of 20 mg/kg every 4 weeks showed a mean absolute dystrophin expression of 8.72% of normal (adjusted for muscle content) at the 6-month time point.

The DELIVER Registrational Expansion Cohort of 32 patients is now fully enrolled, with data expected in late 2025. Dyne anticipates a potential BLA submission for US accelerated approval for DYNE-251 in early 2026, based on dystrophin expression as a surrogate biomarker. The company believes that if approved, DYNE-251 has the potential for rapid adoption in the DMD community. BMO Capital Markets initiated coverage on Dyne on March 12 with an Outperform rating and a $50 price target.

While we acknowledge the growth potential of Dyne Therapeutics Inc. (NASDAQ:DYN), our conviction lies in the belief that AI stocks hold great promise for delivering high returns and doing so within a shorter time frame. There is an AI stock that went up since the beginning of 2025, while popular AI stocks lost around 25%. If you are looking for an AI stock that is more promising than DYN but that trades at less than 5 times its earnings, check out our report about this cheapest AI stock.

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