8. LSD
Street names: Window, Tripper, Smilies, Rainbows, Lightning Flash
LSD was accidentally synthesized in 1938 by Albert Hofmann. Prior to becoming illegal, LSD was used on psychiatric patients. In the USA it was an extremely popular drug that left its mark on hippy movement. In Global Drug Survey, 10.1 percent of respondents reported using LSD. In the USA 1.1 million people used LSD. It remains unclear how LSD exactly affects the brain, but it is known that it is similar to serotonin, which is a reason why it activates serotonin receptors in the brain. In recent years, some researchers have focused on LSD medical use in lowering anxiety and alleviating pain.