8. St. Louis, Missouri
The number of new businesses has been on the rise since 2009 in St Louis. Nine years ago the city was 11 percent below the national average in the number of new firms per 100,000 people, while now it has the fifth highest startup density (96.7) among largest cities in America. Moreover, the money invested in new businesses went from $66 million in 2013 to $176 million in 2015. The greatest number of startups have been launched in the IT and biotechnology sector. Low business costs coupled with good access to human and financial resources have placed St Louis at the seventh spot on the WalletHub’s list. On the other hand the city is positioned relatively low on Kauffman’s ranking but it is worth noting that it has made the greatest progress between 2016 and 2017, advancing from 36th to 26th place.
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