10 Worst High-Risk High-Reward Growth Stocks To Buy

1. Twist Bioscience Corporation (NASDAQ:TWST)

Beta (5Y Monthly): 2.15

3-Year Sales Growth: 31.20%

Number of Hedge Fund Holders: 26

Analyst Upside Potential: 36.99%

Twist Bioscience Corporation (NASDAQ:TWST) is a synthetic biology and genomics company that has developed a proprietary DNA synthesis platform to industrialize the engineering of biology. The company’s core technology includes manufacturing synthetic DNA by writing it on a silicon chip. It is also exploring innovative applications like DNA-based digital data storage and biologics drug discovery.

On March 5, TD Cowen analyst Brendan Smith maintained a Buy rating on the stocks with a price target of $58. During the fiscal first quarter of 2025, Twist Bioscience Corporation (NASDAQ:TWST) reported a strong financial and operational performance, showcasing growth across its core business segments and advancements in its proprietary DNA synthesis platform. The company achieved $88.7 million in revenue for the quarter, marking a 24% year-over-year increase and 5% sequential growth. Moreover, the gross margins also improved significantly to 48.3%, up from 40.5% in the prior quarter. This growth was driven by higher volumes and cost-optimization efforts. In addition, approximately 75-80% of incremental revenue contributed directly to gross margin.

Looking ahead, it remains focused on achieving adjusted EBITDA breakeven without raising additional capital and while continuing to invest in profitable growth opportunities. It is the worst high-growth high-reward growth stock to buy.

While we acknowledge the potential of Twist Bioscience Corporation (NASDAQ:TWST) to grow, our conviction lies in the belief that AI stocks hold greater promise for delivering higher returns and doing so within a shorter time frame. If you are looking for an AI stock that is more promising than TWST but that trades at less than 5 times its earnings, check out our report about the cheapest AI stock.

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