5. Duke University
STD rate: 991
Coming in halfway on our list of colleges with the highest STD rates in America is Duke University that found its place on our list because it is one of the least healthiest universities in the United States. The sexual health rate at Duke University is 3.47% and 991 people per 100,000 have an STD. This means the number of people who have an STD is +138% more than the national average. 12.6 per 10,000 people have STDs as a result of a sexual assault which is +103% more than the national average.